Johannes Hebebrand Selected Research

Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)

1/2020	Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI-SDS-A case series.
4/2019	Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS After a Lifestyle Intervention.
1/2013	Successful treatment with atomoxetine of an adolescent boy with attention deficit/hyperactivity disorder, extreme obesity, and reduced melanocortin 4 receptor function.
5/2012	Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through.
6/2011	Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder.
1/2011	Common variants near MC4R: exploring gender effects in overweight and obese children and adolescents participating in a lifestyle intervention.
11/2010	Investigation of a genome wide association signal for obesity: synthetic association and haplotype analyses at the melanocortin 4 receptor gene locus.
4/2010	Sympathetic function in human carriers of melanocortin-4 receptor gene mutations.
3/2010	Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals.
2/2010	Changes of peripheral alpha-melanocyte-stimulating hormone in childhood obesity.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Johannes Hebebrand Research Topics

Disease

56	Obesity 01/2024 - 06/2002
34	Anorexia Nervosa 02/2024 - 12/2002
26	Body Weight (Weight, Body) 01/2024 - 07/2002
12	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 03/2024 - 06/2011
12	Weight Loss (Weight Reduction) 02/2024 - 06/2004
10	Weight Gain 01/2023 - 09/2004
9	Starvation 02/2024 - 04/2005
9	Feeding and Eating Disorders (Eating Disorder) 02/2024 - 06/2003
8	Overweight 01/2021 - 06/2007
8	Mental Disorders (Mental Disorder) 12/2020 - 10/2010
5	Tourette Syndrome (Tourette's Syndrome) 11/2013 - 05/2004
5	Insulin Resistance 02/2012 - 04/2009
4	Vitamin D Deficiency 07/2021 - 09/2017
4	Hyperphagia (Overeating) 01/2020 - 04/2005
4	Schizophrenia (Dementia Praecox) 10/2019 - 09/2004
4	Pediatric Obesity 12/2011 - 06/2008
4	Type 2 Diabetes Mellitus (MODY) 06/2011 - 06/2002
4	Bulimia Nervosa 10/2009 - 06/2003
4	Anorexia 04/2006 - 06/2003
3	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021 - 05/2003
3	Inflammation (Inflammations) 10/2020 - 02/2012
3	Food Addiction 11/2018 - 01/2012
2	Morbid Obesity 01/2023 - 01/2020
2	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 03/2020
2	Dyslipidemias (Dyslipidemia) 01/2021 - 01/2019
2	Abdominal Obesity 04/2019 - 05/2006
2	Amenorrhea 01/2019 - 01/2009
2	Hypertension (High Blood Pressure) 01/2019 - 04/2010
2	Psychomotor Agitation (Akathisia) 08/2006 - 11/2003
2	Bulimia (Binge Eating) 06/2004 - 08/2003
1	Sleep Wake Disorders 01/2023
1	Epstein-Barr Virus Infections 01/2023
1	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2023
1	Hypogonadism (Hypergonadotropic Hypogonadism) 10/2022
1	Chronic Renal Insufficiency 01/2022
1	Autism Spectrum Disorder 01/2022
1	Lipodystrophy 01/2022
1	Fatigue 01/2020

Drug/Important Bio-Agent (IBA)

26	LeptinIBA 02/2024 - 06/2003
18	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 01/2020 - 08/2003
10	metreleptinIBA 02/2024 - 01/2019
8	Insulin (Novolin)FDA Link 02/2012 - 01/2008
6	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022 - 06/2007
5	Vitamin D FDA LinkGeneric 08/2021 - 09/2017
5	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 09/2008
5	GhrelinIBA 05/2011 - 06/2002
5	Antipsychotic Agents (Antipsychotics)IBA 07/2009 - 09/2004
4	Leptin ReceptorsIBA 02/2024 - 12/2012
4	MelanocortinsIBA 01/2024 - 02/2010
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2014
4	hydroxide ionIBA 08/2021 - 05/2019
4	Neurotransmitter Agents (Neurotransmitter)IBA 01/2016 - 01/2004
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 06/2011 - 06/2004
3	Triglycerides (Triacylglycerol)IBA 01/2021 - 09/2008
3	LipidsIBA 01/2021 - 02/2012
3	Methylphenidate (Ritalin)FDA LinkGeneric 01/2020 - 06/2011
3	Hormones (Hormone)IBA 01/2012 - 05/2006
3	Ghrelin ReceptorsIBA 05/2011 - 01/2004
3	Clozapine (Clozaril)FDA LinkGeneric 12/2005 - 09/2004
2	Lipocalin-2IBA 01/2023 - 04/2019
2	Antidepressive Agents (Antidepressants)IBA 01/2022 - 03/2020
2	LipopolysaccharidesIBA 10/2020 - 01/2020
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 01/2013
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2018 - 06/2007
2	ORALIT (ORS)IBA 01/2016 - 10/2009
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2016 - 02/2006
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 06/2013 - 12/2011
2	DNA (Deoxyribonucleic Acid)IBA 05/2013 - 04/2006
2	Growth Hormone (Somatotropin)IBA 05/2011 - 06/2007
2	Biological FactorsIBA 10/2010 - 09/2009
2	Nerve Growth Factors (Neurotrophins)IBA 10/2010 - 05/2008
2	gastric inhibitory polypeptide receptorIBA 08/2010 - 03/2009
2	AntigensIBA 04/2010 - 05/2003
2	alpha-MSHIBA 02/2010 - 02/2006
2	Serotonin ReceptorsIBA 10/2009 - 12/2005
2	Serotonin (5 Hydroxytryptamine)IBA 10/2009 - 09/2004
2	Dietary Fats (Dietary Fat)IBA 01/2009 - 06/2005
2	Topiramate (Topamax)FDA LinkGeneric 07/2008 - 12/2002
2	Cannabinoid Receptors (Cannabinoid Receptor)IBA 04/2007 - 05/2004
1	Testosterone (Sustanon)FDA Link 03/2024
1	AdipokinesIBA 01/2023
1	CreatineIBA 01/2023
1	Type 3 Melanocortin ReceptorIBA 01/2023
1	Complement System Proteins (Complement)IBA 01/2023
1	Semaphorin-3AIBA 12/2022
1	SteroidsIBA 01/2022
1	Circular RNAIBA 01/2022
1	Cholecalciferol (Vitamin D3)FDA Link 12/2020
1	CytokinesIBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	C-Reactive ProteinIBA 10/2019
1	Leucine (L-Leucine)FDA Link 10/2019

Therapy/Procedure

7	Therapeutics 01/2023 - 08/2005
2	Bariatric Surgery 01/2021 - 07/2020
2	Intravenous Injections 10/2020 - 01/2020
1	Combined Modality Therapy 11/2022
1	Ambulatory Care (Outpatient Care) 11/2022
1	Caloric Restriction 10/2022
1	Aftercare (After-Treatment) 12/2019